Each year on 11 February, the International Day of Women and Girls in Science provides an opportunity to recognise the fundamental role women play in advancing scientific knowledge and to encourage future generations of girls to pursue careers in research and innovation. 

In the field of dementia and Alzheimer’s disease, many of the advances achieved over recent decades are closely linked to the work of women scientists whose contributions have shaped both biomedical research and public health strategies. Today, we want to highlight Rita Levi-Montalcini and Martha Clare Morris as key figures whose legacy continues to influence current approaches to brain health. 

Rita Levi-Montalcini: biological foundations of neurodegeneration research 

Rita Levi-Montalcini, Italian neurobiologist and Nobel Prize in Physiology or Medicine, made an important contribution to neuroscience with the discovery of the Nerve Growth Factor (NGF). Her research changed the understanding of how neurons develop, survive and age, providing a scientific basis for studying neurodegenerative processes. 

Her work has had long-lasting implications for Alzheimer’s research, particularly in relation to neuronal vulnerability, brain plasticity and mechanisms of neuroprotection.  

Beyond her scientific achievements, Rita Levi-Montalcini was a strong advocate for education, scientific culture and the role of women in research. Throughout her life, she promoted the idea that scientific knowledge should serve society and contribute to long-term social progress.

Martha Clare Morris: translating evidence into prevention strategies 

From a public health and epidemiological perspective, Martha Clare Morris brought prevention to the centre of Alzheimer’s research. Her work focused on the relationship between diet, lifestyle and cognitive decline, analysing how modifiable factors can influence brain health over time. 

As the creator of the MIND diet, she demonstrated that specific dietary patterns are associated with a lower risk of Alzheimer’s disease and slower cognitive decline. This evidence-based approach helped bridge the gap between research and everyday life, reinforcing the role of prevention strategies within public health policies. 

Her contribution has been instrumental in framing Alzheimer’s prevention as a shared responsibility between health systems and individuals, highlighting the importance of early-life and mid-life interventions to support healthy ageing. 

Inspiring future generations and advancing brain health in Europe 

The scientific paths of Rita Levi-Montalcini and Martha Clare Morris reflect two complementary pillars in addressing dementia: advancing fundamental knowledge of brain biology and promoting evidence-based prevention strategies at population level. 

In the context of the International Day of Women and Girls in Science, JADE Health recognises this legacy and reaffirms its commitment to research, prevention, early detection and equity in brain health. By making women scientists visible, JADE Health contributes to inspiring future generations and to strengthening sustainable, people-centred health systems across Europe.